| ( ! ) Warning: Undefined variable $axeSDesc in /var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/app/src/Project/Helpers.php on line 43 |
|---|
| Call Stack |
|---|
| # | Time | Memory | Function | Location |
|---|
| 1 | 0.0001 | 359672 | {main}( ) | .../index.php:0 |
| 2 | 0.0002 | 361024 | require( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-blog-header.php ) | .../index.php:17 |
| 3 | 1.0567 | 105001512 | require_once( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/template-loader.php ) | .../wp-blog-header.php:19 |
| 4 | 1.0731 | 105341840 | apply_filters( $hook_name = 'template_include', $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-video-library.blade.php' ) | .../template-loader.php:114 |
| 5 | 1.0731 | 105342248 | WP_Hook->apply_filters( $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-video-library.blade.php', $args = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-video-library.blade.php'] ) | .../plugin.php:205 |
| 6 | 1.0731 | 105343784 | Magina\StarterTheme\Template\Hooks->render( $template = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-video-library.blade.php' ) | .../class-wp-hook.php:341 |
| 7 | 1.1727 | 107832696 | Magina\StarterTheme\Template\Helpers::render( $template = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-video-library.blade.php', $data = ['override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }] ) | .../Hooks.php:121 |
| 8 | 1.1728 | 107832784 | Jenssegers\Blade\Blade->render( $view = 'single-video-library', $data = ['override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }], $mergeData = ??? ) | .../Helpers.php:48 |
| 9 | 1.1747 | 107890768 | Illuminate\View\View->render( $callback = ??? ) | .../Blade.php:47 |
| 10 | 1.1747 | 107890768 | Illuminate\View\View->renderContents( ) | .../View.php:91 |
| 11 | 1.1747 | 107890824 | Illuminate\View\View->getContents( ) | .../View.php:122 |
| 12 | 1.1747 | 107891520 | Illuminate\View\Engines\CompilerEngine->get( $path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', $data = ['__env' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $compiler = class Illuminate\View\Compilers\BladeCompiler { ... }; protected $lastCompiled = [...] }] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $paths = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views']; protected $views = ['single-video-library' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', 'partials.page-header' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/page-header.blade.php', 'partials.breadcrumb' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/breadcrumb.blade.php', 'partials.loop.project' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php']; protected $hints = []; protected $extensions = [0 => 'blade.php', 1 => 'php', 2 => 'css', 3 => 'html'] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = []; protected $bindings = []; protected $methodBindings = []; protected $instances = []; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [], 'composing: single-video-library' => [], 'creating: partials.page-header' => [], 'composing: partials.page-header' => [], 'creating: partials.breadcrumb' => [], 'composing: partials.breadcrumb' => [], 'creating: partials.loop.project' => [], 'composing: partials.loop.project' => []]; protected $queueResolver = NULL }; protected $container = class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [...], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = [...]; protected $customDirectives = [...]; protected $conditions = [...]; protected $precompilers = [...]; protected $path = NULL; protected $compilers = [...]; protected $rawTags = [...]; protected $contentTags = [...]; protected $escapedTags = [...]; protected $echoFormat = 'e(%s)'; protected $footer = [...]; protected $rawBlocks = [...]; protected $classComponentAliases = [...]; protected $classComponentNamespaces = [...]; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = [...]; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $shared = ['__env' => ..., 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => [...], 'events' => [...], 'config' => [...], 'view' => [...], 'view.finder' => [...], 'blade.compiler' => [...], 'view.engine.resolver' => [...]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { ... }, 'files' => class Illuminate\Filesystem\Filesystem { ... }, 'config' => [...], 'events' => class Illuminate\Events\Dispatcher { ... }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { ... }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $static = [...]; public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { ... }] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views'], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = [...]; protected $bindings = [...]; protected $methodBindings = [...]; protected $instances = [...]; protected $scopedInstances = [...]; protected $aliases = [...]; protected $abstractAliases = [...]; protected $extenders = [...]; protected $tags = [...]; protected $buildStack = [...]; protected $with = [...]; public $contextual = [...]; protected $reboundCallbacks = [...]; protected $globalBeforeResolvingCallbacks = [...]; protected $globalResolvingCallbacks = [...]; protected $globalAfterResolvingCallbacks = [...]; protected $beforeResolvingCallbacks = [...]; protected $resolvingCallbacks = [...]; protected $afterResolvingCallbacks = [...] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [...], 'composing: single-video-library' => [...], 'creating: partials.page-header' => [...], 'composing: partials.page-header' => [...], 'creating: partials.breadcrumb' => [...], 'composing: partials.breadcrumb' => [...], 'creating: partials.loop.project' => [...], 'composing: partials.loop.project' => [...]]; protected $queueResolver = NULL }, 'view' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $paths = [...]; protected $views = [...]; protected $hints = [...]; protected $extensions = [...] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }; protected $container = ...; protected $shared = ['__env' => ..., 'app' => ...]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = []; protected $customDirectives = ['asset' => [...], 'shortcode' => [...], 'debug' => [...], 'svg' => [...]]; protected $conditions = []; protected $precompilers = []; protected $path = NULL; protected $compilers = [0 => 'Extensions', 1 => 'Statements', 2 => 'Echos']; protected $rawTags = [0 => '{!!', 1 => '!!}']; protected $contentTags = [0 => '{{', 1 => '}}']; protected $escapedTags = [0 => '{{{', 1 => '}}}']; protected $echoFormat = 'e(%s)'; protected $footer = []; protected $rawBlocks = []; protected $classComponentAliases = ['dynamic-component' => 'Illuminate\\View\\DynamicComponent']; protected $classComponentNamespaces = []; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = []; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }, 'override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }] ) | .../View.php:139 |
| 13 | 1.1748 | 107892216 | Illuminate\View\Engines\PhpEngine->evaluatePath( $path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache/99959100aa5db5b06d6ff30b783f4db1635206cf.php', $data = ['__env' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $compiler = class Illuminate\View\Compilers\BladeCompiler { ... }; protected $lastCompiled = [...] }] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $paths = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views']; protected $views = ['single-video-library' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', 'partials.page-header' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/page-header.blade.php', 'partials.breadcrumb' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/breadcrumb.blade.php', 'partials.loop.project' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php']; protected $hints = []; protected $extensions = [0 => 'blade.php', 1 => 'php', 2 => 'css', 3 => 'html'] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = []; protected $bindings = []; protected $methodBindings = []; protected $instances = []; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [], 'composing: single-video-library' => [], 'creating: partials.page-header' => [], 'composing: partials.page-header' => [], 'creating: partials.breadcrumb' => [], 'composing: partials.breadcrumb' => [], 'creating: partials.loop.project' => [], 'composing: partials.loop.project' => []]; protected $queueResolver = NULL }; protected $container = class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [...], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = [...]; protected $customDirectives = [...]; protected $conditions = [...]; protected $precompilers = [...]; protected $path = NULL; protected $compilers = [...]; protected $rawTags = [...]; protected $contentTags = [...]; protected $escapedTags = [...]; protected $echoFormat = 'e(%s)'; protected $footer = [...]; protected $rawBlocks = [...]; protected $classComponentAliases = [...]; protected $classComponentNamespaces = [...]; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = [...]; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $shared = ['__env' => ..., 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => [...], 'events' => [...], 'config' => [...], 'view' => [...], 'view.finder' => [...], 'blade.compiler' => [...], 'view.engine.resolver' => [...]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { ... }, 'files' => class Illuminate\Filesystem\Filesystem { ... }, 'config' => [...], 'events' => class Illuminate\Events\Dispatcher { ... }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { ... }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $static = [...]; public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { ... }] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views'], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = [...]; protected $bindings = [...]; protected $methodBindings = [...]; protected $instances = [...]; protected $scopedInstances = [...]; protected $aliases = [...]; protected $abstractAliases = [...]; protected $extenders = [...]; protected $tags = [...]; protected $buildStack = [...]; protected $with = [...]; public $contextual = [...]; protected $reboundCallbacks = [...]; protected $globalBeforeResolvingCallbacks = [...]; protected $globalResolvingCallbacks = [...]; protected $globalAfterResolvingCallbacks = [...]; protected $beforeResolvingCallbacks = [...]; protected $resolvingCallbacks = [...]; protected $afterResolvingCallbacks = [...] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [...], 'composing: single-video-library' => [...], 'creating: partials.page-header' => [...], 'composing: partials.page-header' => [...], 'creating: partials.breadcrumb' => [...], 'composing: partials.breadcrumb' => [...], 'creating: partials.loop.project' => [...], 'composing: partials.loop.project' => [...]]; protected $queueResolver = NULL }, 'view' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $paths = [...]; protected $views = [...]; protected $hints = [...]; protected $extensions = [...] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }; protected $container = ...; protected $shared = ['__env' => ..., 'app' => ...]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = []; protected $customDirectives = ['asset' => [...], 'shortcode' => [...], 'debug' => [...], 'svg' => [...]]; protected $conditions = []; protected $precompilers = []; protected $path = NULL; protected $compilers = [0 => 'Extensions', 1 => 'Statements', 2 => 'Echos']; protected $rawTags = [0 => '{!!', 1 => '!!}']; protected $contentTags = [0 => '{{', 1 => '}}']; protected $escapedTags = [0 => '{{{', 1 => '}}}']; protected $echoFormat = 'e(%s)'; protected $footer = []; protected $rawBlocks = []; protected $classComponentAliases = ['dynamic-component' => 'Illuminate\\View\\DynamicComponent']; protected $classComponentNamespaces = []; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = []; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }, 'override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }] ) | .../CompilerEngine.php:61 |
| 14 | 1.1748 | 107908728 | Illuminate\Filesystem\Filesystem->getRequire( $path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache/99959100aa5db5b06d6ff30b783f4db1635206cf.php', $data = ['__env' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $compiler = class Illuminate\View\Compilers\BladeCompiler { ... }; protected $lastCompiled = [...] }] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $paths = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views']; protected $views = ['single-video-library' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', 'partials.page-header' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/page-header.blade.php', 'partials.breadcrumb' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/breadcrumb.blade.php', 'partials.loop.project' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php']; protected $hints = []; protected $extensions = [0 => 'blade.php', 1 => 'php', 2 => 'css', 3 => 'html'] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = []; protected $bindings = []; protected $methodBindings = []; protected $instances = []; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [], 'composing: single-video-library' => [], 'creating: partials.page-header' => [], 'composing: partials.page-header' => [], 'creating: partials.breadcrumb' => [], 'composing: partials.breadcrumb' => [], 'creating: partials.loop.project' => [], 'composing: partials.loop.project' => []]; protected $queueResolver = NULL }; protected $container = class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [...], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = [...]; protected $customDirectives = [...]; protected $conditions = [...]; protected $precompilers = [...]; protected $path = NULL; protected $compilers = [...]; protected $rawTags = [...]; protected $contentTags = [...]; protected $escapedTags = [...]; protected $echoFormat = 'e(%s)'; protected $footer = [...]; protected $rawBlocks = [...]; protected $classComponentAliases = [...]; protected $classComponentNamespaces = [...]; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = [...]; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $shared = ['__env' => ..., 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => [...], 'events' => [...], 'config' => [...], 'view' => [...], 'view.finder' => [...], 'blade.compiler' => [...], 'view.engine.resolver' => [...]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { ... }, 'files' => class Illuminate\Filesystem\Filesystem { ... }, 'config' => [...], 'events' => class Illuminate\Events\Dispatcher { ... }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { ... }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $static = [...]; public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { ... }] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views'], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = [...]; protected $bindings = [...]; protected $methodBindings = [...]; protected $instances = [...]; protected $scopedInstances = [...]; protected $aliases = [...]; protected $abstractAliases = [...]; protected $extenders = [...]; protected $tags = [...]; protected $buildStack = [...]; protected $with = [...]; public $contextual = [...]; protected $reboundCallbacks = [...]; protected $globalBeforeResolvingCallbacks = [...]; protected $globalResolvingCallbacks = [...]; protected $globalAfterResolvingCallbacks = [...]; protected $beforeResolvingCallbacks = [...]; protected $resolvingCallbacks = [...]; protected $afterResolvingCallbacks = [...] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [...], 'composing: single-video-library' => [...], 'creating: partials.page-header' => [...], 'composing: partials.page-header' => [...], 'creating: partials.breadcrumb' => [...], 'composing: partials.breadcrumb' => [...], 'creating: partials.loop.project' => [...], 'composing: partials.loop.project' => [...]]; protected $queueResolver = NULL }, 'view' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $paths = [...]; protected $views = [...]; protected $hints = [...]; protected $extensions = [...] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }; protected $container = ...; protected $shared = ['__env' => ..., 'app' => ...]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = []; protected $customDirectives = ['asset' => [...], 'shortcode' => [...], 'debug' => [...], 'svg' => [...]]; protected $conditions = []; protected $precompilers = []; protected $path = NULL; protected $compilers = [0 => 'Extensions', 1 => 'Statements', 2 => 'Echos']; protected $rawTags = [0 => '{!!', 1 => '!!}']; protected $contentTags = [0 => '{{', 1 => '}}']; protected $escapedTags = [0 => '{{{', 1 => '}}}']; protected $echoFormat = 'e(%s)'; protected $footer = []; protected $rawBlocks = []; protected $classComponentAliases = ['dynamic-component' => 'Illuminate\\View\\DynamicComponent']; protected $classComponentNamespaces = []; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = []; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }, 'override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }] ) | .../PhpEngine.php:58 |
| 15 | 1.1748 | 107909488 | Illuminate\Filesystem\Filesystem::Illuminate\Filesystem\{closure:/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/vendor/illuminate/filesystem/Filesystem.php:104-108}( ) | .../Filesystem.php:108 |
| 16 | 1.1749 | 107923208 | require( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/resources/uploads/cache/99959100aa5db5b06d6ff30b783f4db1635206cf.php ) | .../Filesystem.php:107 |
| 17 | 1.1772 | 107950160 | Illuminate\View\View->render( $callback = ??? ) | .../99959100aa5db5b06d6ff30b783f4db1635206cf.php:20 |
| 18 | 1.1772 | 107950160 | Illuminate\View\View->renderContents( ) | .../View.php:91 |
| 19 | 1.1773 | 107950224 | Illuminate\View\View->getContents( ) | .../View.php:122 |
| 20 | 1.1773 | 107950920 | Illuminate\View\Engines\CompilerEngine->get( $path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php', $data = ['__env' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $compiler = class Illuminate\View\Compilers\BladeCompiler { ... }; protected $lastCompiled = [...] }] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $paths = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views']; protected $views = ['single-video-library' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', 'partials.page-header' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/page-header.blade.php', 'partials.breadcrumb' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/breadcrumb.blade.php', 'partials.loop.project' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php']; protected $hints = []; protected $extensions = [0 => 'blade.php', 1 => 'php', 2 => 'css', 3 => 'html'] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = []; protected $bindings = []; protected $methodBindings = []; protected $instances = []; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [], 'composing: single-video-library' => [], 'creating: partials.page-header' => [], 'composing: partials.page-header' => [], 'creating: partials.breadcrumb' => [], 'composing: partials.breadcrumb' => [], 'creating: partials.loop.project' => [], 'composing: partials.loop.project' => []]; protected $queueResolver = NULL }; protected $container = class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [...], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = [...]; protected $customDirectives = [...]; protected $conditions = [...]; protected $precompilers = [...]; protected $path = NULL; protected $compilers = [...]; protected $rawTags = [...]; protected $contentTags = [...]; protected $escapedTags = [...]; protected $echoFormat = 'e(%s)'; protected $footer = [...]; protected $rawBlocks = [...]; protected $classComponentAliases = [...]; protected $classComponentNamespaces = [...]; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = [...]; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $shared = ['__env' => ..., 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => [...], 'events' => [...], 'config' => [...], 'view' => [...], 'view.finder' => [...], 'blade.compiler' => [...], 'view.engine.resolver' => [...]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { ... }, 'files' => class Illuminate\Filesystem\Filesystem { ... }, 'config' => [...], 'events' => class Illuminate\Events\Dispatcher { ... }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { ... }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $static = [...]; public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { ... }] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views'], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = [...]; protected $bindings = [...]; protected $methodBindings = [...]; protected $instances = [...]; protected $scopedInstances = [...]; protected $aliases = [...]; protected $abstractAliases = [...]; protected $extenders = [...]; protected $tags = [...]; protected $buildStack = [...]; protected $with = [...]; public $contextual = [...]; protected $reboundCallbacks = [...]; protected $globalBeforeResolvingCallbacks = [...]; protected $globalResolvingCallbacks = [...]; protected $globalAfterResolvingCallbacks = [...]; protected $beforeResolvingCallbacks = [...]; protected $resolvingCallbacks = [...]; protected $afterResolvingCallbacks = [...] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [...], 'composing: single-video-library' => [...], 'creating: partials.page-header' => [...], 'composing: partials.page-header' => [...], 'creating: partials.breadcrumb' => [...], 'composing: partials.breadcrumb' => [...], 'creating: partials.loop.project' => [...], 'composing: partials.loop.project' => [...]]; protected $queueResolver = NULL }, 'view' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $paths = [...]; protected $views = [...]; protected $hints = [...]; protected $extensions = [...] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }; protected $container = ...; protected $shared = ['__env' => ..., 'app' => ...]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = []; protected $customDirectives = ['asset' => [...], 'shortcode' => [...], 'debug' => [...], 'svg' => [...]]; protected $conditions = []; protected $precompilers = []; protected $path = NULL; protected $compilers = [0 => 'Extensions', 1 => 'Statements', 2 => 'Echos']; protected $rawTags = [0 => '{!!', 1 => '!!}']; protected $contentTags = [0 => '{{', 1 => '}}']; protected $escapedTags = [0 => '{{{', 1 => '}}}']; protected $echoFormat = 'e(%s)'; protected $footer = []; protected $rawBlocks = []; protected $classComponentAliases = ['dynamic-component' => 'Illuminate\\View\\DynamicComponent']; protected $classComponentNamespaces = []; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = []; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }, 'override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'showAxe' => TRUE] ) | .../View.php:139 |
| 21 | 1.1774 | 107951080 | Illuminate\View\Engines\PhpEngine->evaluatePath( $path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache/58e71303448da4a5f8cfa0b20dbd5468bf1ead2a.php', $data = ['__env' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $compiler = class Illuminate\View\Compilers\BladeCompiler { ... }; protected $lastCompiled = [...] }] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $paths = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views']; protected $views = ['single-video-library' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', 'partials.page-header' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/page-header.blade.php', 'partials.breadcrumb' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/breadcrumb.blade.php', 'partials.loop.project' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php']; protected $hints = []; protected $extensions = [0 => 'blade.php', 1 => 'php', 2 => 'css', 3 => 'html'] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = []; protected $bindings = []; protected $methodBindings = []; protected $instances = []; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [], 'composing: single-video-library' => [], 'creating: partials.page-header' => [], 'composing: partials.page-header' => [], 'creating: partials.breadcrumb' => [], 'composing: partials.breadcrumb' => [], 'creating: partials.loop.project' => [], 'composing: partials.loop.project' => []]; protected $queueResolver = NULL }; protected $container = class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [...], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = [...]; protected $customDirectives = [...]; protected $conditions = [...]; protected $precompilers = [...]; protected $path = NULL; protected $compilers = [...]; protected $rawTags = [...]; protected $contentTags = [...]; protected $escapedTags = [...]; protected $echoFormat = 'e(%s)'; protected $footer = [...]; protected $rawBlocks = [...]; protected $classComponentAliases = [...]; protected $classComponentNamespaces = [...]; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = [...]; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $shared = ['__env' => ..., 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => [...], 'events' => [...], 'config' => [...], 'view' => [...], 'view.finder' => [...], 'blade.compiler' => [...], 'view.engine.resolver' => [...]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { ... }, 'files' => class Illuminate\Filesystem\Filesystem { ... }, 'config' => [...], 'events' => class Illuminate\Events\Dispatcher { ... }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { ... }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $static = [...]; public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { ... }] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views'], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = [...]; protected $bindings = [...]; protected $methodBindings = [...]; protected $instances = [...]; protected $scopedInstances = [...]; protected $aliases = [...]; protected $abstractAliases = [...]; protected $extenders = [...]; protected $tags = [...]; protected $buildStack = [...]; protected $with = [...]; public $contextual = [...]; protected $reboundCallbacks = [...]; protected $globalBeforeResolvingCallbacks = [...]; protected $globalResolvingCallbacks = [...]; protected $globalAfterResolvingCallbacks = [...]; protected $beforeResolvingCallbacks = [...]; protected $resolvingCallbacks = [...]; protected $afterResolvingCallbacks = [...] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [...], 'composing: single-video-library' => [...], 'creating: partials.page-header' => [...], 'composing: partials.page-header' => [...], 'creating: partials.breadcrumb' => [...], 'composing: partials.breadcrumb' => [...], 'creating: partials.loop.project' => [...], 'composing: partials.loop.project' => [...]]; protected $queueResolver = NULL }, 'view' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $paths = [...]; protected $views = [...]; protected $hints = [...]; protected $extensions = [...] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }; protected $container = ...; protected $shared = ['__env' => ..., 'app' => ...]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = []; protected $customDirectives = ['asset' => [...], 'shortcode' => [...], 'debug' => [...], 'svg' => [...]]; protected $conditions = []; protected $precompilers = []; protected $path = NULL; protected $compilers = [0 => 'Extensions', 1 => 'Statements', 2 => 'Echos']; protected $rawTags = [0 => '{!!', 1 => '!!}']; protected $contentTags = [0 => '{{', 1 => '}}']; protected $escapedTags = [0 => '{{{', 1 => '}}}']; protected $echoFormat = 'e(%s)'; protected $footer = []; protected $rawBlocks = []; protected $classComponentAliases = ['dynamic-component' => 'Illuminate\\View\\DynamicComponent']; protected $classComponentNamespaces = []; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = []; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }, 'override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'showAxe' => TRUE] ) | .../CompilerEngine.php:61 |
| 22 | 1.1774 | 107967592 | Illuminate\Filesystem\Filesystem->getRequire( $path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache/58e71303448da4a5f8cfa0b20dbd5468bf1ead2a.php', $data = ['__env' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $compiler = class Illuminate\View\Compilers\BladeCompiler { ... }; protected $lastCompiled = [...] }] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $paths = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views']; protected $views = ['single-video-library' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/single-video-library.blade.php', 'partials.page-header' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/page-header.blade.php', 'partials.breadcrumb' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/breadcrumb.blade.php', 'partials.loop.project' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources/views/partials/loop/project.blade.php']; protected $hints = []; protected $extensions = [0 => 'blade.php', 1 => 'php', 2 => 'css', 3 => 'html'] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = []; protected $bindings = []; protected $methodBindings = []; protected $instances = []; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [], 'composing: single-video-library' => [], 'creating: partials.page-header' => [], 'composing: partials.page-header' => [], 'creating: partials.breadcrumb' => [], 'composing: partials.breadcrumb' => [], 'creating: partials.loop.project' => [], 'composing: partials.loop.project' => []]; protected $queueResolver = NULL }; protected $container = class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", ... }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [...], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = [...]; protected $customDirectives = [...]; protected $conditions = [...]; protected $precompilers = [...]; protected $path = NULL; protected $compilers = [...]; protected $rawTags = [...]; protected $contentTags = [...]; protected $escapedTags = [...]; protected $echoFormat = 'e(%s)'; protected $footer = [...]; protected $rawBlocks = [...]; protected $classComponentAliases = [...]; protected $classComponentNamespaces = [...]; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = [...]; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }; protected $shared = ['__env' => ..., 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => [...], 'events' => [...], 'config' => [...], 'view' => [...], 'view.finder' => [...], 'blade.compiler' => [...], 'view.engine.resolver' => [...]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { ... }, 'files' => class Illuminate\Filesystem\Filesystem { ... }, 'config' => [...], 'events' => class Illuminate\Events\Dispatcher { ... }, 'view' => ..., 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { ... }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'app' => class Illuminate\Container\Container { protected $resolved = ['view.engine.resolver' => TRUE, 'files' => TRUE, 'config' => TRUE, 'view.finder' => TRUE, 'events' => TRUE, 'view' => TRUE, 'blade.compiler' => TRUE]; protected $bindings = ['files' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'events' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'config' => ['concrete' => class Closure { virtual $closure = "$this->Jenssegers\Blade\{closure}", public $static = [...]; public $this = class Jenssegers\Blade\Blade { ... } }, 'shared' => TRUE], 'view' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.finder' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => FALSE], 'blade.compiler' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... }; public $parameter = [...] }, 'shared' => TRUE], 'view.engine.resolver' => ['concrete' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", public $this = class Illuminate\View\ViewServiceProvider { ... } }, 'shared' => TRUE]]; protected $methodBindings = []; protected $instances = ['view.engine.resolver' => class Illuminate\View\Engines\EngineResolver { protected $resolvers = ['file' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'php' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }, 'blade' => class Closure { virtual $closure = "$this->Illuminate\View\{closure}", ... }]; protected $resolved = ['blade' => class Illuminate\View\Engines\CompilerEngine { ... }] }, 'files' => class Illuminate\Filesystem\Filesystem { }, 'config' => ['view.paths' => [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views'], 'view.compiled' => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'], 'events' => class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { protected $resolved = [...]; protected $bindings = [...]; protected $methodBindings = [...]; protected $instances = [...]; protected $scopedInstances = [...]; protected $aliases = [...]; protected $abstractAliases = [...]; protected $extenders = [...]; protected $tags = [...]; protected $buildStack = [...]; protected $with = [...]; public $contextual = [...]; protected $reboundCallbacks = [...]; protected $globalBeforeResolvingCallbacks = [...]; protected $globalResolvingCallbacks = [...]; protected $globalAfterResolvingCallbacks = [...]; protected $beforeResolvingCallbacks = [...]; protected $resolvingCallbacks = [...]; protected $afterResolvingCallbacks = [...] }; protected $listeners = []; protected $wildcards = []; protected $wildcardsCache = ['creating: single-video-library' => [...], 'composing: single-video-library' => [...], 'creating: partials.page-header' => [...], 'composing: partials.page-header' => [...], 'creating: partials.breadcrumb' => [...], 'composing: partials.breadcrumb' => [...], 'creating: partials.loop.project' => [...], 'composing: partials.loop.project' => [...]]; protected $queueResolver = NULL }, 'view' => class Illuminate\View\Factory { protected $engines = class Illuminate\View\Engines\EngineResolver { protected $resolvers = [...]; protected $resolved = [...] }; protected $finder = class Illuminate\View\FileViewFinder { protected $files = class Illuminate\Filesystem\Filesystem { ... }; protected $paths = [...]; protected $views = [...]; protected $hints = [...]; protected $extensions = [...] }; protected $events = class Illuminate\Events\Dispatcher { protected $container = class Illuminate\Container\Container { ... }; protected $listeners = [...]; protected $wildcards = [...]; protected $wildcardsCache = [...]; protected $queueResolver = NULL }; protected $container = ...; protected $shared = ['__env' => ..., 'app' => ...]; protected $extensions = ['blade.php' => 'blade', 'php' => 'php', 'css' => 'file', 'html' => 'file']; protected $composers = []; protected $renderCount = 2; protected $renderedOnce = []; protected $componentStack = []; protected $componentData = []; protected $currentComponentData = []; protected $slots = []; protected $slotStack = []; protected $sections = []; protected $sectionStack = [0 => 'content']; protected $loopsStack = []; protected $pushes = []; protected $prepends = []; protected $pushStack = []; protected $translationReplacements = [] }, 'blade.compiler' => class Illuminate\View\Compilers\BladeCompiler { protected $files = class Illuminate\Filesystem\Filesystem { }; protected $cachePath = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/uploads/cache'; protected $extensions = []; protected $customDirectives = ['asset' => [...], 'shortcode' => [...], 'debug' => [...], 'svg' => [...]]; protected $conditions = []; protected $precompilers = []; protected $path = NULL; protected $compilers = [0 => 'Extensions', 1 => 'Statements', 2 => 'Echos']; protected $rawTags = [0 => '{!!', 1 => '!!}']; protected $contentTags = [0 => '{{', 1 => '}}']; protected $escapedTags = [0 => '{{{', 1 => '}}}']; protected $echoFormat = 'e(%s)'; protected $footer = []; protected $rawBlocks = []; protected $classComponentAliases = ['dynamic-component' => 'Illuminate\\View\\DynamicComponent']; protected $classComponentNamespaces = []; protected $compilesComponentTags = TRUE; protected $firstCaseInSwitch = TRUE; protected $echoHandlers = []; private $encodingOptions = 15; protected $lastSection = NULL; protected $forElseCounter = 0 }]; protected $scopedInstances = []; protected $aliases = []; protected $abstractAliases = []; protected $extenders = []; protected $tags = []; protected $buildStack = []; protected $with = []; public $contextual = []; protected $reboundCallbacks = []; protected $globalBeforeResolvingCallbacks = []; protected $globalResolvingCallbacks = []; protected $globalAfterResolvingCallbacks = []; protected $beforeResolvingCallbacks = []; protected $resolvingCallbacks = []; protected $afterResolvingCallbacks = [] }, 'override' => 'app', 'display_sidebar' => FALSE, 'breadLinks' => [], 'bgHeader' => '', 'bgHeaderMobile' => '', 'bgLink' => '', 'isEvaluator' => FALSE, 'isAdmin' => FALSE, 'relatedPjs' => class WP_Query { public $query = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742']]; public $query_vars = ['post_type' => 'project', 'posts_per_page' => -1, 'post__in' => [0 => '35742'], 'error' => '', 'm' => '', 'p' => 0, 'post_parent' => '', 'subpost' => '', 'subpost_id' => '', 'attachment' => '', 'attachment_id' => 0, 'name' => '', 'pagename' => '', 'page_id' => 0, 'second' => '', 'minute' => '', 'hour' => '', 'day' => 0, 'monthnum' => 0, 'year' => 0, 'w' => 0, 'category_name' => '', 'tag' => '', 'cat' => '', 'tag_id' => '', 'author' => '', 'author_name' => '', 'feed' => '', 'tb' => '', 'paged' => 0, 'meta_key' => '', 'meta_value' => '', 'preview' => '', 's' => '', 'sentence' => '', 'title' => '', 'fields' => 'all', 'menu_order' => '', 'embed' => '', 'category__in' => [], 'category__not_in' => [], 'category__and' => [], 'post__not_in' => [], 'post_name__in' => [], 'tag__in' => [], 'tag__not_in' => [], 'tag__and' => [], 'tag_slug__in' => [], 'tag_slug__and' => [], 'post_parent__in' => [], 'post_parent__not_in' => [], 'author__in' => [], 'author__not_in' => [], 'search_columns' => [], 'ignore_sticky_posts' => FALSE, 'suppress_filters' => FALSE, 'cache_results' => TRUE, 'update_post_term_cache' => TRUE, 'update_menu_item_cache' => FALSE, 'lazy_load_term_meta' => TRUE, 'update_post_meta_cache' => TRUE, 'nopaging' => TRUE, 'comments_per_page' => '50', 'no_found_rows' => FALSE, 'order' => 'DESC']; public $tax_query = class WP_Tax_Query { public $queries = []; public $relation = 'AND'; protected $table_aliases = []; public $queried_terms = []; public $primary_table = 'wp_posts'; public $primary_id_column = 'ID' }; public $meta_query = class WP_Meta_Query { public $queries = []; public $relation = NULL; public $meta_table = NULL; public $meta_id_column = NULL; public $primary_table = NULL; public $primary_id_column = NULL; protected $table_aliases = []; protected $clauses = []; protected $has_or_relation = FALSE }; public $date_query = FALSE; public $queried_object = *uninitialized*; public $queried_object_id = *uninitialized*; public $request = 'SELECT wp_posts.*\n\t\t\t\t\t FROM wp_posts \n\t\t\t\t\t WHERE 1=1 AND wp_posts.ID IN (35742) AND ((wp_posts.post_type = \'project\' AND (wp_posts.post_status = \'publish\')))\n\t\t\t\t\t \n\t\t\t\t\t ORDER BY wp_posts.post_date DESC\n\t\t\t\t\t '; public $posts = [0 => class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }]; public $post_count = 1; public $current_post = 0; public $before_loop = FALSE; public $in_the_loop = TRUE; public $post = class WP_Post { public $ID = 35742; public $post_author = '36'; public $post_date = '2025-03-13 09:46:17'; public $post_date_gmt = '2025-03-13 08:46:17'; public $post_content = 'L’immunothérapie anticancéreuse, notamment via les inhibiteurs des points de contrôle immunitaire, présente une efficacité limitée en raison de l’immunosuppression du microenvironnement tumoral. Pour surmonter cette résistance, nous avons développé des immunoliposomes chargés de valrubicine (Val-ILs) capables de cibler plusieurs types de cellules immunosuppressives simultanément, une avancée par rapport aux approches actuelles qui se limitent généralement à une ou deux populations cellulaires. Testés sur un modèle murin 4T1 du cancer du sein triple négatif, ces Val-ILs réduisent significativement la progression tumorale et les métastases. De plus, leur association avec l’anti-PD1 entraîne une régression complète du développement tumoral dans 62,5 % des cas. A ce jour, aucune thérapie clinique n’exploite les immunoliposomes. Grâce à leur composition en lipides biocompatibles et à une faible concentration de valrubicine, les Val-ILs s’accumulent dans la rate, où ils induis'...; public $post_title = 'Etude préclinique avec des nanoparticules lipidiques chargées d\'un agent antitumoral et fonctionnalisées pour cibler les cellules immunosuppressives dans les traitements du cancer du sein triple négatif'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-03 15:52:43'; public $post_modified_gmt = '2025-11-03 14:52:43'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/projets/etude-preclinique-avec-des-nanoparticules-lipidiques-chargees-dun-agent-antitumoral-et-fonctionnalisees-pour-cibler-les-cellules-immunosuppressives-dans-les-traitements-du-cancer-du-sein-triple-nega/'; public $menu_order = 0; public $post_type = 'project'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }; public $comments = *uninitialized*; public $comment_count = 0; public $current_comment = -1; public $comment = *uninitialized*; public $found_posts = 1; public $max_num_pages = 0; public $max_num_comment_pages = 0; public $is_single = FALSE; public $is_preview = FALSE; public $is_page = FALSE; public $is_archive = TRUE; public $is_date = FALSE; public $is_year = FALSE; public $is_month = FALSE; public $is_day = FALSE; public $is_time = FALSE; public $is_author = FALSE; public $is_category = FALSE; public $is_tag = FALSE; public $is_tax = FALSE; public $is_search = FALSE; public $is_feed = FALSE; public $is_comment_feed = FALSE; public $is_trackback = FALSE; public $is_home = FALSE; public $is_privacy_policy = FALSE; public $is_404 = FALSE; public $is_embed = FALSE; public $is_paged = FALSE; public $is_admin = FALSE; public $is_attachment = FALSE; public $is_singular = FALSE; public $is_robots = FALSE; public $is_favicon = FALSE; public $is_posts_page = FALSE; public $is_post_type_archive = TRUE; private $query_vars_hash = 'f22cbfee58af7ba92bdb3b2a722a268b'; private $query_vars_changed = FALSE; public $thumbnails_cached = FALSE; protected $allow_query_attachment_by_filename = FALSE; private $stopwords = NULL; private $compat_fields = [0 => 'query_vars_hash', 1 => 'query_vars_changed']; private $compat_methods = [0 => 'init_query_flags', 1 => 'parse_tax_query']; private $query_cache_key = 'wp_query:9cedcd9f3dd760520458deef953d96da' }, 'prev' => class WP_Post { public $ID = 36771; public $post_author = '1'; public $post_date = '2025-10-31 10:25:10'; public $post_date_gmt = '2025-10-31 09:25:10'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Isabelle Lamsoul'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-isabelle-lamsoul'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-10-31 10:25:58'; public $post_modified_gmt = '2025-10-31 09:25:58'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36771'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'next' => class WP_Post { public $ID = 36776; public $post_author = '1'; public $post_date = '2025-11-06 14:37:26'; public $post_date_gmt = '2025-11-06 13:37:26'; public $post_content = ''; public $post_title = 'Découvrez l\'interview de Nathalie Chaput'; public $post_excerpt = ''; public $post_status = 'publish'; public $comment_status = 'closed'; public $ping_status = 'closed'; public $post_password = ''; public $post_name = 'decouvrez-linterview-de-nathalie-chaput'; public $to_ping = ''; public $pinged = ''; public $post_modified = '2025-11-06 14:37:26'; public $post_modified_gmt = '2025-11-06 13:37:26'; public $post_content_filtered = ''; public $post_parent = 0; public $guid = 'https://fondation-bms.ontest.net/?post_type=video-library&p=36776'; public $menu_order = 0; public $post_type = 'video-library'; public $post_mime_type = ''; public $comment_count = '0'; public $filter = 'raw' }, 'showAxe' => TRUE] ) | .../PhpEngine.php:58 |
| 23 | 1.1774 | 107968352 | Illuminate\Filesystem\Filesystem::Illuminate\Filesystem\{closure:/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/vendor/illuminate/filesystem/Filesystem.php:104-108}( ) | .../Filesystem.php:108 |
| 24 | 1.1775 | 107979648 | require( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/resources/uploads/cache/58e71303448da4a5f8cfa0b20dbd5468bf1ead2a.php ) | .../Filesystem.php:107 |
| 25 | 1.1782 | 108060128 | App\Project\Helpers::getInfos( $postID = 35742 ) | .../58e71303448da4a5f8cfa0b20dbd5468bf1ead2a.php:1 |
