( ! ) Notice: La fonction WP_Scripts::localize a été appelée de façon <strong>incorrecte</strong>. Le paramètre <code>$l10n</code> doit être un tableau. Pour transmettre des données arbitraires aux scripts, utilisez plutôt la fonction <code>wp_add_inline_script()</code>. Veuillez lire <a href="https://developer.wordpress.org/advanced-administration/debug/debug-wordpress/">Débogage dans WordPress</a> (en) pour plus d’informations. (Ce message a été ajouté à la version 5.7.0.) in /var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/functions.php on line 6131
Call Stack
#TimeMemoryFunctionLocation
10.0001360536{main}( ).../index.php:0
20.0002361888require( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-blog-header.php ).../index.php:17
31.1539104989976require_once( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/template-loader.php ).../wp-blog-header.php:19
41.1837105489648apply_filters( $hook_name = 'template_include', $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php' ).../template-loader.php:114
51.1837105490056WP_Hook->apply_filters( $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php', $args = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php'] ).../plugin.php:205
61.1838105491592Magina\StarterTheme\Template\Hooks->render( $template = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php' ).../class-wp-hook.php:341
71.1838105492072Illuminate\Support\Collection->each( $callback = class Closure { virtual $closure = "$this->Magina\StarterTheme\Template\{closure}", public $this = class Magina\StarterTheme\Template\Hooks { }; public $parameter = ['$tag' => '<required>'] } ).../Hooks.php:115
81.1838105495416Magina\StarterTheme\Template\Hooks->Magina\StarterTheme\Template\{closure:/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/vendor/magina/starter-theme-templating-module/src/Hooks.php:107-115}( $tag = 'wp_head', 1 ).../EnumeratesValues.php:245
91.1838105512184do_action( $hook_name = 'wp_head' ).../Hooks.php:109
101.1838105512560WP_Hook->do_action( $args = [0 => ''] ).../plugin.php:522
111.1838105512560WP_Hook->apply_filters( $value = '', $args = [0 => ''] ).../class-wp-hook.php:365
121.1839105515016wp_enqueue_scripts( '' ).../class-wp-hook.php:341
131.1839105515016do_action( $hook_name = 'wp_enqueue_scripts' ).../script-loader.php:2311
141.1839105519488WP_Hook->do_action( $args = [0 => ''] ).../plugin.php:522
151.1839105519488WP_Hook->apply_filters( $value = '', $args = [0 => ''] ).../class-wp-hook.php:365
161.2129105899608App\Setup\Hooks->enqueueAssets( '' ).../class-wp-hook.php:341
171.2130105899712wp_localize_script( $handle = 'scripts/pages/app.compiled.js', $object_name = 'adminAjax', $l10n = 'https://fondation-bms.ontest.net/wp-admin/admin-ajax.php' ).../Hooks.php:138
181.2130105899712WP_Scripts->localize( $handle = 'scripts/pages/app.compiled.js', $object_name = 'adminAjax', $l10n = 'https://fondation-bms.ontest.net/wp-admin/admin-ajax.php' ).../functions.wp-scripts.php:233
191.2130105900032_doing_it_wrong( $function_name = 'WP_Scripts::localize', $message = 'Le paramètre <code>$l10n</code> doit être un tableau. Pour transmettre des données arbitraires aux scripts, utilisez plutôt la fonction <code>wp_add_inline_script()</code>.', $version = '5.7.0' ).../class-wp-scripts.php:616
201.2131105901376wp_trigger_error( $function_name = '', $message = 'La fonction WP_Scripts::localize a été appelée de façon <strong>incorrecte</strong>. Le paramètre <code>$l10n</code> doit être un tableau. Pour transmettre des données arbitraires aux scripts, utilisez plutôt la fonction <code>wp_add_inline_script()</code>. Veuillez lire <a href="https://developer.wordpress.org/advanced-administration/debug/debug-wordpress/">Débogage dans WordPress</a> (en) pour plus d’informations. (Ce message a été ajouté à la version 5.7.0.)', $error_level = ??? ).../functions.php:6071
211.2133105901848trigger_error( $message = 'La fonction WP_Scripts::localize a été appelée de façon <strong>incorrecte</strong>. Le paramètre <code>$l10n</code> doit être un tableau. Pour transmettre des données arbitraires aux scripts, utilisez plutôt la fonction <code>wp_add_inline_script()</code>. Veuillez lire <a href="https://developer.wordpress.org/advanced-administration/debug/debug-wordpress/">Débogage dans WordPress</a> (en) pour plus d’informations. (Ce message a été ajouté à la version 5.7.0.)', $error_level = 1024 ).../functions.php:6131
Essai d’escalade de dose (phase I/II), évaluant l'innocuité et l'efficacité de l’Ipilimumab en Intra-arteriel (IA) en combinaison avec le Nivolumab intra-veineux (IV) chez les patients atteints d’hépatocarcinome à un stade avancé. - Fondation BMS
( ! ) Notice: file_get_contents(): Read of 8192 bytes failed with errno=21 Is a directory in /var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/functions.php on line 4681
Call Stack
#TimeMemoryFunctionLocation
10.0001360536{main}( ).../index.php:0
20.0002361888require( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-blog-header.php ).../index.php:17
31.1539104989976require_once( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/template-loader.php ).../wp-blog-header.php:19
41.1837105489648apply_filters( $hook_name = 'template_include', $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php' ).../template-loader.php:114
51.1837105490056WP_Hook->apply_filters( $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php', $args = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php'] ).../plugin.php:205
61.1838105491592Magina\StarterTheme\Template\Hooks->render( $template = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php' ).../class-wp-hook.php:341
71.1838105492072Illuminate\Support\Collection->each( $callback = class Closure { virtual $closure = "$this->Magina\StarterTheme\Template\{closure}", public $this = class Magina\StarterTheme\Template\Hooks { }; public $parameter = ['$tag' => '<required>'] } ).../Hooks.php:115
81.1838105495416Magina\StarterTheme\Template\Hooks->Magina\StarterTheme\Template\{closure:/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/vendor/magina/starter-theme-templating-module/src/Hooks.php:107-115}( $tag = 'wp_head', 1 ).../EnumeratesValues.php:245
91.1838105512184do_action( $hook_name = 'wp_head' ).../Hooks.php:109
101.1838105512560WP_Hook->do_action( $args = [0 => ''] ).../plugin.php:522
111.1838105512560WP_Hook->apply_filters( $value = '', $args = [0 => ''] ).../class-wp-hook.php:365
121.2585107356584wp_print_font_faces( $fonts = '' ).../class-wp-hook.php:341
131.2585107356584WP_Font_Face_Resolver::get_fonts_from_theme_json( ).../fonts.php:46
141.2585107356584wp_get_global_settings( $path = ???, $context = ??? ).../class-wp-font-face-resolver.php:29
151.2586107356640WP_Theme_JSON_Resolver::get_merged_data( $origin = 'custom' ).../global-styles-and-settings.php:80
161.2785107909496WP_Theme_JSON_Resolver::get_theme_data( $deprecated = ???, $options = ??? ).../class-wp-theme-json-resolver.php:668
171.2787107910136WP_Theme_JSON_Resolver::read_json_file( $file_path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources' ).../class-wp-theme-json-resolver.php:255
181.2787107910136wp_json_file_decode( $filename = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources', $options = ['associative' => TRUE] ).../class-wp-theme-json-resolver.php:110
191.2787107910624file_get_contents( $filename = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources' ).../functions.php:4681

( ! ) Notice: wp_json_file_decode(): Erreur lors du décodage du fichier JSON à l’emplacement /var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources : Syntax error in /var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/functions.php on line 6131
Call Stack
#TimeMemoryFunctionLocation
10.0001360536{main}( ).../index.php:0
20.0002361888require( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-blog-header.php ).../index.php:17
31.1539104989976require_once( '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-includes/template-loader.php ).../wp-blog-header.php:19
41.1837105489648apply_filters( $hook_name = 'template_include', $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php' ).../template-loader.php:114
51.1837105490056WP_Hook->apply_filters( $value = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php', $args = [0 => '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php'] ).../plugin.php:205
61.1838105491592Magina\StarterTheme\Template\Hooks->render( $template = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources/views/single-project.blade.php' ).../class-wp-hook.php:341
71.1838105492072Illuminate\Support\Collection->each( $callback = class Closure { virtual $closure = "$this->Magina\StarterTheme\Template\{closure}", public $this = class Magina\StarterTheme\Template\Hooks { }; public $parameter = ['$tag' => '<required>'] } ).../Hooks.php:115
81.1838105495416Magina\StarterTheme\Template\Hooks->Magina\StarterTheme\Template\{closure:/var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/vendor/magina/starter-theme-templating-module/src/Hooks.php:107-115}( $tag = 'wp_head', 1 ).../EnumeratesValues.php:245
91.1838105512184do_action( $hook_name = 'wp_head' ).../Hooks.php:109
101.1838105512560WP_Hook->do_action( $args = [0 => ''] ).../plugin.php:522
111.1838105512560WP_Hook->apply_filters( $value = '', $args = [0 => ''] ).../class-wp-hook.php:365
121.2585107356584wp_print_font_faces( $fonts = '' ).../class-wp-hook.php:341
131.2585107356584WP_Font_Face_Resolver::get_fonts_from_theme_json( ).../fonts.php:46
141.2585107356584wp_get_global_settings( $path = ???, $context = ??? ).../class-wp-font-face-resolver.php:29
151.2586107356640WP_Theme_JSON_Resolver::get_merged_data( $origin = 'custom' ).../global-styles-and-settings.php:80
161.2785107909496WP_Theme_JSON_Resolver::get_theme_data( $deprecated = ???, $options = ??? ).../class-wp-theme-json-resolver.php:668
171.2787107910136WP_Theme_JSON_Resolver::read_json_file( $file_path = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources' ).../class-wp-theme-json-resolver.php:255
181.2787107910136wp_json_file_decode( $filename = '/var/www/vhosts/fondation-bms.ontest.net/httpdocs/wp/wp-content/themes/fondation-bms/resources', $options = ['associative' => TRUE] ).../class-wp-theme-json-resolver.php:110
191.2799107935880wp_trigger_error( $function_name = 'wp_json_file_decode', $message = 'Erreur lors du décodage du fichier JSON à l’emplacement /var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources : Syntax error', $error_level = ??? ).../functions.php:4690
201.2800107936200trigger_error( $message = 'wp_json_file_decode(): Erreur lors du décodage du fichier JSON à l’emplacement /var/www/vhosts/fondation-bms.ontest.net/httpdocs/src/themes/fondation-bms/resources : Syntax error', $error_level = 1024 ).../functions.php:6131

Essai d’escalade de dose (phase I/II), évaluant l’innocuité et l’efficacité de l’Ipilimumab en Intra-arteriel (IA) en combinaison avec le Nivolumab intra-veineux (IV) chez les patients atteints d’hépatocarcinome à un stade avancé.

L’administration locale d’immunomodulateurs a pour objectif de déclencher une réponse immunitaire systémique spécifique. L’injection intra-artérielle (IA) d’anticorps pourrait pallier aux problématiques liées à l’administration systémique (résistance, toxicité) et l’injection intratumorale (IT) percutanée (accessibilité des tumeurs et répartition du traitement variables). Notre projet a pour objectif d’évaluer l’administration IA d’Ipilimumab, sous guidage radiologique, en combinaison avec du Nivolumab en intraveineux chez les patients porteurs de CHC avancé. Le rationnel étant d’exposer la tumeur ainsi que son environnement à une plus forte concentration locale d’Ipilimumab tout en maintenant un bon profil de toxicité. La tolérance, la dose mais aussi l’efficacité et les modifications immunologiques induites seront évaluées.

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